BDBM50187114 CHEMBL3823303

SMILES CCc1cc(Nc2ncc(F)c(n2)-c2cnc3cccnn23)cc(OCCN2CCC(O)CC2)c1

InChI Key InChIKey=VZWXALUQDOYOJQ-UHFFFAOYSA-N

Data  5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187114   

TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL

LigandBDBM50187114(CHEMBL3823303)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL

LigandBDBM50187114(CHEMBL3823303)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI